Ale sells for 20 and only requires Mugs, which in turn only require 1 玻璃, which is crafted from only 2 沙 each. Each unit of 2 Sand is therefore worth 20 if used to craft Ale. Crafting Ale can ultimately be the most profitable means of selling off Sand without incorporating other ingredients.
Since the ale provides a debuff, using the 护士 will charge players more for getting healed and will remove the debuff as well.
Drinking ale then using the nurse is an effective way to get the "The Frequent Flyer" achievement.